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Doubters Welcome!—Clarifying Our Numbers For The Backlog

September 4, 2012 by · Leave a Comment 


Since August 2011, we’ve publicly speculated about a backlog of 30,000 Iraqi children in need of lifesaving heart surgery. After decades of war and sanctions, in a country that lacks a national registry for heart defects, have you ever wondered where The Backlog numbers come from? Here’s a peek behind the curtain…

UNICEF states the approximate number of children born in Iraq in 2010 was 1,125,000i. Numerous studiesii estimate the normal rate of children born with congenital heart defects (CHD) to be somewhere between 6-10 out of every 1,000 children. As a percentage, that is somewhere between 0.6% and 1% “incidence.”

That means that every year in Iraq, between 6,750 and 11,250 children are born with congenital heart defects.

However, there are other factors that potentially raise the incidence of CHD in Iraq beyond 1%. Some of these factors include increased rates of diabetes, vitamin deficienciesiii, intrafamily marriageiv, and environmental exposuresv. It’s difficult to know exactly how much all of this combined would raise the incidence of CHD in Iraq. But we can confidently assume that at least 11,000 children are born with heart defects every year in Iraq, based on the incidence and amount of children born.


Thankfully, not every child born with CHD will have severe enough defects to require surgery. But somewhere between 25-50% of those 11,000 children will need surgery or else they will dievi. Sadly, the healthcare infrastructure in Iraq was decimated by sanctions, war, and internal strife and no longer has the ability to reduce its backlog or operate on new children born with CHD. Every year, 90% of the children in Iraq fail to receive the surgeries they require to survive.vii

Each new year, up to 5,500 new children will need surgery. This is what we call The Backlog. Unfortunately, some 31% of all children born with CHD will die in the first year without surgery; they would not make it to the next year’s backlog. Similarly, many infants die from other causes, so that would also lower the amount of children on the backlog. Amazingly, some children heal on their own.

When children come off the backlog from these, or any other, causes it’s called attrition. While it’s hard to measure the rate of attrition, it’s almost insignificant if we assume an incidence rate higher than 1%. If we simply began (albeit arbitrarily) with the beginning of the Iraq War in 2003, our estimates above would place The Backlog between 22,000 and 44,000 kids. That averages to around 33,000 children who need surgeries to survive.viii

This is why we work so hard each day to train Iraqi doctors and nurses across the country—it is only by establishing local heart care centers that these children will be served as they are born and the future buildup of The Backlog will be avoided!

References:

i Iraq: Statistics. UNICEF. Accessed on 4 June 2012

ii Hoffman, J. I., & Kaplan, S. (2002). The incidence of congenital heart disease. Journal of the American College of Cardiology, 39(12), 1890-1900.

iii ILDP, The Status of Women in Iraq: Update to the Assessment of Iraq’s De Jure and De Facto Compliance with International Standards, December 2006, pg. 45

iv “Al-Ani ZR. Association of consanguinity with congenital heart diseases in a teaching hospital in western iraq. Saudi Med J. 2010 Sep;31(9):1021-7.

v Jenkins KJ, Correa A, Feinstein JA, Botto L, Britt AE, Daniels SR, et al. Noninherited risk factors and congenital cardiovascular defects: Current knowledge. Circulation. 2007 June 12;115(23):2995-3014.

vi “Mitchell, S.C, Korones, S.B., & Berendes, H.W. Congenital Heart Disease in 56,109 Births Incidence and Natural History. Circulation, 1971; 43:323-332

vii Based on PLC surveys conducted with government officials, cardiologists and surgeons across Iraq.

viii The actual number may be less due to our inability to calculate real attrition and our inability (as yet) to estimate the actual increased incidence due to extraordinary factors in Iraq. We do not want to engage in hyperbole or sensationalism. But we choose the higher side of the spectrum because our mandate requires us to help the Ministry of Health establish a sufficient number of surgery centers across the country. Choosing the high number will not cause us to develop too many centers, but choosing the lower end of the spectrum might very well cause us to develop too few.

 width= Alicia Lay is a Texan, foodie, and atypical medical student who is interning as a medical researcher as she works towards her Master’s in Public Health. She is passionate about international medicine, surgery, public health, and Iraqi children. When not in a hospital or doing research on the computer, she enjoys taking photos, reading about global health, and singing the day away as if her life were a musical.

We’re Making History—Three “Firsts” In One Week!

July 20, 2012 by · Leave a Comment 

This has been an amazing week!
It was so exciting to be a part of Remedy Mission X. It feels like I hear about new firsts every day:

We’re the first American team to come to Fallujah General Hospital since the war.

This is the first cardiac catheterization lab built in the hospital’s history.

This week was the first time the lab is used.

But most exciting of all: this is PLC’s first Remedy Mission in Fallujah. It’s been a week of history in the making!

Some of the most exciting firsts involved the groundbreaking catheterization procedures (‘caths’). We treated 12 children over the week and the first three days gave us a chance to break the cath lab in.

Sweet little Balkis about to get his operation at Fallujah General Hospital.
On the first day of the mission, we performed the FIRST diagnostic cath on 2 year-old Balkis. He has two holes in his heart, known as ventricular septal defects (VSDs). The doctors knew he had these holes because of an ECHO screening done by a local Iraqi cardiologist and verified by Dr. Kirk on our first day in Fallujah. To fix them, Balkis will need surgery. But the surgeons have to know lots of detailed information about the hole and the status of his heart and lungs. The diagnostic cath provided that information.

Balkis can now safely have surgery at any hospital because his parents can take the cath report to any heart surgeon and they’ll know exactly what they need to know!

A photo of a little girl named Sara, the first to have her heart fixed in the history of Anbar Province!
The second day we performed the FIRST PDA closure in 13 year-old Sara. A PDA (patent ductus arteriosus) is an abnormal connection between the two biggest vessels coming off the heart. However, a simple coil placed in the PDA acts as a plug that closes the connection.

It’s incredible that such a tiny piece of metal could have INSTANT results in changing the blood flow in Sara’s heart. Before her cath, I could literally feel the vibrations of blood flowing abnormally. But immediately afterwards, her heart felt normal! Amazing! She is the first of many more children to be cured by caths in Fallujah General Hospital!

A photo of 5 year-old Rawan on the scale before she heads into the operating room.
The third day, we performed the FIRST heart valve widening on 5 year old Rawan. Her pulmonary valve was too small for blood to flow smoothly which could have led to heart failure. However, Rawan was treated by a cath that used a balloon to physically stretch out the valve. Now the blood can flow normally, and Rawan can be active and play without her heart getting tired out!

All of these “firsts” were exciting for the local Iraqi medical staff, local and international news agencies, and government officials. But despite the thrill of being a part of a “first”, the greatest impact of the new cath lab won’t be seen for years to come, after countless more children undergo procedures at Fallujah General.

Each child who received a cath had their lives changed forever, especially those who received interventional procedures. To them, it didn’t matter whether they were the first or the last, it just mattered that they were able to be treated.

We have the amazing opportunity to change the course of history here in Fallujah and it’s thanks to your support—thank you for making this trip possible! We helped 12 children and spread goodwill through their families on your behalf, and we can’t wait to come back!

An image of a needle and thread stitching a heart. Our 85 suture kits are FULLY funded — Thank you for helping fund $765 worth of medical supplies!





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 width= Alicia Lay is a Texan, foodie, and atypical medical student who is interning as a medical researcher as she works towards her Master’s in Public Health. She is passionate about international medicine, surgery, public health, and Iraqi children. When not in a hospital or doing research on the computer, she enjoys taking photos, reading about global health, and singing the day away as if her life were a musical.

What Is Happening To Babies In Fallujah, Iraq?

June 21, 2012 by · Leave a Comment 

A baby stares at the camera surrounded by medical equipment. Recently, an article was published in a well-known medical journal about the rate of congenital birth defects in Fallujah, Iraq.

Fallujah saw some of the most intense fighting during the Iraq War, so the long-term effects of war are important to research in this area. According to the article, “in May 2010, over 15% of all deliveries (547) in Fallujah General Hospital presented birth defects.”1 This is much higher than in the rest of the world, which usually only has around 3% of babies being born with birth defects.2 The most common types of abnormalities in Fallujah were congenital heart defects (CHD).

The report describes four families living in Fallujah, and each of these families had at least one child with birth defects. Several questions were asked to the parents to identify possible exposure to toxic chemicals in the air they breathe, the dirt they walk on, the water they drink, or food they eat. This may include being close to chemical weapons and bombings, smoking and drinking habits of the parents, and a history of where they lived before, during, and after the war.

The results suggest that chemicals and metals from the Iraq War may have led to birth defects in the Iraqi children born during the conflict. The contaminants did not necessarily have an immediate effect on the parents. However, continued exposure to toxins over a long period of time and a build-up of the toxins in the parent’s body could lead to birth defects in their children.

Read the article for yourself here.

This report is of absolute importance in figuring out why there is such a large backlog of Iraqi children needing heart surgery. It encourages specific possible sources leading to higher numbers of birth defects. This is incredibly important because if we find out why, then maybe we can prevent defects from occurring in babies being born in the future.

References:

1Alaani S, Savabieasfahani M, Tafash M, Manduca P. Four polygamous families with congenital birth defects from Fallujah, Iraq. Int J Environ Res Publ Health 2011; 8:89-96

2 Update on overall prevalence of major birth defects—Atlanta, Georgia, 1978-2005.MMWR Morb Mortal Wkly Rep 2008;57:1-5.

 width= Alicia Lay is a Texan, foodie, and atypical medical student who is interning as a medical researcher as she works towards her Master’s in Public Health. She is passionate about international medicine, surgery, public health, and Iraqi children. When not in a hospital or doing research on the computer, she enjoys taking photos, reading about global health, and singing the day away as if her life were a musical.

Counting Kids: Researching Heart Defects in Dohuk

June 12, 2012 by · Leave a Comment 

Alicia and Dr. Kirk

Right off the bat, I got to be a part of something awesome here in Iraq.

I joined PLC’s groundbreaking research in the city of Dohuk in Iraqi Kurdistan. Many reports in recent years claim that there are more heart defects in Iraq than other countries in the Middle East. In Fallujah, news reports state 10 times more birth defects than the world average. However, these numbers are based on general observations, not a systematic study. Is it possible that doctors who only see sick children would think there are many more birth defects than there really are?

The best way to find out if there are more kids being born with broken hearts is to count all the children who are born, then see how many have heart defects are detected. That way, the number of healthy babies can be compared to the number of babies with defects to get an accurate ratio of sick to healthy babies. This is exactly what we did in the city of Dohuk.

Dr. Kirk scans a baby, another doctor looks on

Alongside long-time friend and partner of PLC, Dr. Kirk Milhoan and Dr. Serdar Pedawi, I was a part of a research team working to identify the heart defect “incidence” or number of new cases of babies born with heart defects out of all babies born over a certain time period. We set up camp at Azadi Teaching Hospital in Dohuk, and every child that was born came to us to be screened for heart defects.

This was done using an echocardiogram (ECHO) machine, which is similar to an ultrasound that allows pregnant mothers to see their babies. It provides a way to look at the heart from the outside, quickly and painlessly. All children born in Azadi Hospital during the week of the study had to be screened in order to obtain their birth certificate, so we were able to screen more than 180 kids!

Each individual encounter was very similar. The moms were usually too worn out from childbirth to bring the babies to us (understandably so!). It fell to the grandmothers and aunts to take care of the newborn while mom got some rest. It was beautiful to see how much love and care was shown to each baby we screened. They were all wrapped tightly in brightly colored clothes and tucked into what I can only describe as a fancy baby sleeping bag.

Aunt and grandmothers at the ready to help

The children truly lived up to the phrase of “bundles of joy.” The pride and joy of family members was evident, but with it came the anxious fear that their baby could have something wrong with their heart. Immediately at the time of the screening we could tell the family the result of the ECHO.

Thankfully, the vast majority of children had completely normal hearts and their family was always relieved and ecstatic to hear the good news. But there were some babies who did indeed have heart defects. Some had leaky heart valves and others had holes in their heart. Assurance was given to the families that these were not immediately life-threatening emergencies, but that their baby needed to be checked again in a few weeks to see what kind of treatment would be needed to live a normal healthy life.

Dr. Serdar works full time as a Pediatric Cardiologist in Dohuk, and thus will take care of these babies directly. Research can sometimes be all about collecting numbers, but this research heavily emphasized providing practical medical care for those who were found to have heart defects.

Dr. Kirk preforms an ECHO on a baby

It was an absolutely incredible experience to interact with the Kurdish and Arab families in Dohuk as well as to be a part of a first-ever scientific study. It was very fulfilling to contribute to the gathering of facts, which is a large part of why I’m pursuing a Master’s in Public Health. Having solid facts puts Preemptive Love Coalition that much closer to eradicating the backlog by treating kids who need lifesaving heart surgeries.

This research is the first step in providing information for the Kurdish Regional and Iraqi Central Government and any other organization that wants an answer to the question: how many Iraqi children are being born with heart defects?

 width= Alicia Lay is a Texan, foodie, and atypical medical student who is interning as a medical researcher as she works towards her Master’s in Public Health. She is passionate about international medicine, surgery, public health, and Iraqi children. When not in a hospital or doing research on the computer, she enjoys taking photos, reading about global health, and singing the day away as if her life were a musical.

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